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Product Name: |
H3K4ME2
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Related proudcts |
histone h4, modification of hist, |
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Synthesized histone H3 peptide corresponding to residues within 1-135 of human histone H3 with dimethylation K4 modification.
SPECIFICATION OF H3K4ME2 CAT H3102 Product&©|160; Name Histone H3-K4me2 Purity ¡Ý95% by HPLC analysis Appearance White powder Usage Research use only Storage Shipping at room temperature. Upon delivery aliquot. Stored at -20℃ or -80℃. Avoid freeze/thaw cycle. Sequence ARTK(me2)QTARKS TGGKAPRKQL ATKAARKSAP ATGGVKKPHR YRPGTVALRE IRRYQKSTEL LIRKLPFQRL VREIAQDFKT DLRFQSSAVM ALQEACEAYL VGLFEDTNLC AIHAKRVTIM PKDIQLARRI RGERA
APPLICATION OF H3K4ME2 H3K4me2 is a modification thought to have a role in transcriptional memory. In CD4+ T lymphocytes, H3K4Me2 is present within gene bodies regulating cellular function, but not in those of housekeeping genes, which indicates that the modification has a role in refining the tissue-specificity of expressed genes. This type of cellular identity targeting is also noted in work with human and mouse spermatozoa; the H3K4Me2 modification marks genes that are relevant in spermatogenesis. Most effects of H3K4Me2 seem to be attributed to its transcriptional activation; however, recent work also indicates that it may also play an RNA-dependent regressive role, related to the GAL-1 promoter.
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Company: |
Hefei KS-V Peptide Biological Technology Co., Ltd.
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Contact: |
KS-V Peptide .com |
Address: |
The 11th floor£¬New Energy Building£¬Institute of Advanced Technology£¬USTC£¬Hefei, Anhui, China |
Postcode: |
2018 |
Tel: |
0551-65120828 |
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